How long does it take for Pepto Bismol to work? (2024)

Medically reviewed by Kristianne Hannemann, PharmD. Last updated on May 22, 2024.

How long does it take for Pepto Bismol to work? (1)

Official answer

by Drugs.com

Pepto-Bismol (also known as the “pink stuff”) is a medication that is commonly used to treat diarrhea and upset stomach. It is available over the counter as an oral liquid, capsules, and chewable tablets. Pepto-Bismol usually works within 30 to 60 minutes.

What is Pepto-Bismol used for?

The active ingredient in Pepto-Bismol, bismuth subsalicylate, works to relieve upset stomach and is also an antidiarrheal. Pepto-Bismol can be taken for the following stomach problems:

  • Traveler’s diarrhea
  • Diarrhea
  • Heartburn
  • Indigestion
  • Nausea
  • Gas
  • Burping
  • Fullness

How often can you take Pepto-Bismol?

Adults and children 12 years and older can take one dose of Pepto-Bismol every 30 to 60 minutes until symptoms improve. Do not take more than 8 doses in 24 hours, and do not take Pepto-Bismol for more than 2 days to treat your symptoms without consulting your doctor.

Make sure to read the instructions on the packaging, since Pepto-Bismol comes as a liquid, capsules, and chewable tablets. This means the amount you need to take for each dose varies.

Pepto-Bismol may not be the best option for everyone. It is not recommended for the following situations:

  • People with an active stomach ulcer, a bleeding problem, or who have bloody or black stools
  • Children or teens who are recovering from chickenpox or flu-like symptoms because of the risk of a serious illness called Reye’s syndrome
  • Pregnant women

Additionally, if you have a fever or mucus in your stool, ask your doctor before using Pepto-Bismol.

Related questions

  • Can you give Pepto Bismol to kids?
  • Why does Pepto-Bismol turn your tongue black?
  • Does Pepto-Bismol help with diarrhea?

Can you take Pepto-Bismol for stomach pain?

Yes. Pepto-Bismol can be used for an upset stomach that is due to eating too much food or drink. However, if your stomach symptoms are not going away after taking Pepto-Bismol or are severe, you should get medical attention.

References

Pepto-Bismol [package insert]. Revised 10/2023. The Procter & Gamble Manufacturing Company - https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=67006e82-870d-8d63-e053-2991aa0a02d1

Centers for Disease Control and Prevention. (Updated June 2022). Pregnant Travelers. Available from: https://wwwnc.cdc.gov/travel/page/pregnant-travelers

Pepto-bismol.com. When and How to Take Pepto Bismol. Accessed May 22, 2024 at https://pepto-bismol.com/en-us/faq/dosage

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Drug information

  • Pepto-Bismol Information for Consumers
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Medical Disclaimer

How long does it take for Pepto Bismol to work? (2024)

FAQs

How long does it take for Pepto Bismol to work? ›

When will I feel better? Pepto-Bismol should work within 30 to 60 minutes. You can have another dose after 30 to 60 minutes, if you need to. You can take up to 8 doses in 24 hours.

How long does it take Pepto-Bismol to kick in? ›

It takes 30 minutes to an hour for Pepto-Bismol (bismuth subsalicylate) to start working and help relieve diarrhea, upset stomach, and nausea. Sometimes referred to as "the pink stuff," Pepto-Bismol is an over-the-counter (OTC) medication that is safe and effective for short-term use.

How long does it take Pepto to clear your system? ›

Pepto-Bismol is usually out of your system in one day, but it can take several days for the side effect to go away.

What to do if Pepto-Bismol doesn't work? ›

If your symptoms have not improved within 2 days, speak to your doctor.

Does Pepto-Bismol really help? ›

This medicine is used for heartburn and acid reflux, indigestion, diarrhoea and feeling sick (nausea). It works by protecting your stomach and the lower part of your food pipe from stomach acid. It is also a mild antacid, which helps reduce too much stomach acid and eases any discomfort.

Should you drink water after taking Pepto-Bismol? ›

When treating diarrhea, be sure to drink plenty of water to replace lost fluid. Keep drinking fluids even if you're using Pepto-Bismol. If your condition lasts longer than 2 days or you have ringing in your ears, stop taking Pepto-Bismol and call your doctor.

What should you not take with Pepto-Bismol? ›

Cautions with other medicines
  • an anticoagulant – medicines that help to prevent blood clots.
  • tablets or other oral medicines for diabetes.
  • medicine for gout.
  • doxycycline or minocycline, or any other tetracycline antibiotics.

What should I drink after taking Pepto-Bismol? ›

You can eat and drink normally while taking Pepto-Bismol. However, it's best to avoid foods that seem to make your indigestion worse, like rich, spicy and fatty foods. Try to cut down on caffeinated drinks, such as tea, coffee, cola and energy drinks.

Is it normal to still have diarrhea after taking Pepto-Bismol? ›

So, if you experience any side effects at all, you should stop using Pepto-Bismol. If you experience diarrhea after starting the medication, it's best to stay well hydrated. The darkening of the tongue or stool is harmless and will resolve on its own within a few days of stopping Pepto-Bismol.

When should you not take Pepto-Bismol? ›

Do not take this medicine if you are pregnant or breastfeeding. Pepto-Bismol is not suitable for some people. To make sure this medicine is safe for you, tell your doctor or pharmacist if you have: ever had an allergic reaction to bismuth subsalicylate or any of the other ingredients in Pepto-Bismol or Pepti Calm.

How can I settle my stomach in 5 minutes? ›

You can also try applying a warm compress to your stomach, such as a heating pad or warm water bottle wrapped in a towel. This can help alleviate pain and cramping. Moreover, drinking a cup of warm water with a teaspoon of honey and a squeeze of lemon juice can help to soothe an upset stomach.

Why doesn't Pepto work for me? ›

Heartburn medication may not work for a few reasons. You may not have acid reflux if your heartburn medication is not working. Other causes may include your diet or incorrectly taking the medication.

What's better, Tums or Pepto? ›

The best upset stomach medicine for you depends on the symptoms you're experiencing and what's causing it. Antacids (such as Tums and Rolaids) are a good choice for heartburn and sour stomach. And medicines that contain bismuth subsalicylate (like Pepto-Bismol) can help treat diarrhea and nausea.

What 5 symptoms does Pepto-Bismol treat? ›

This medication is used to treat occasional upset stomach, heartburn, and nausea. It is also used to treat diarrhea and help prevent travelers' diarrhea. It works by helping to slow the growth of bacteria that might be causing the diarrhea.

Should I take Pepto or let it run its course? ›

Try an over-the-counter drug, such as Immodium A-D, Kaopectate or Pepto-Bismol. Wait at least 12 hours before taking these medicines, though. Let the diarrhea "run its course" to get rid of what caused it.

Can you take Pepto-Bismol on an empty stomach? ›

If you are taking the chewable tablet, take this medication on an empty stomach. The chewable tablets should be chewed thoroughly before swallowing.

Will Pepto-Bismol prolong a stomach virus? ›

However, in some cases, Pepto-Bismol may prolong a stomach virus. This is because diarrhea is the body's way of getting rid of the virus, and treating diarrhea may slow this process down. Most of the time, a stomach virus will resolve on its own with at-home care.

Will Pepto stop diarrhea? ›

Imodium A-D and Pepto-Bismol are effective and convenient treatment options for diarrhea in adults. They can help to lower the frequency of watery and loose stools. And Pepto-Bismol can provide relief for an upset stomach, too. However, they're not meant to treat all types of diarrhea.

References

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